Informatics Service Tender

Informatics Service Tender

UK Biobank is issuing this tender to invite bids to supply large-scale, specialist Whole Genome Sequencing (WGS) Vanguard Informatics.

United Kingdom-Stockport: Data-processing services

2019/S 020-043469

Contract notice

Services

Legal Basis:

Directive 2014/24/EU

Section I: Contracting authority

I.1)Name and addresses

UK Biobank Ltd
1-2 Spectrum Way, Adswood
Stockport
SK3 0SA
United Kingdom
Telephone: +44 1614755386
E-mail: tenders@ukbiobank.ac.uk
NUTS code: UKD3
Internet address(es):Main address: http://www.ukbiobank.ac.ukAddress of the buyer profile: https://www.mytenders.co.uk/search/Search_AuthProfile.aspx?ID=AA25607

I.2)Information about joint procurement

I.3)Communication

The procurement documents are available for unrestricted and full direct access, free of charge, at: https://www.mytenders.co.uk/
Additional information can be obtained from the abovementioned address
Tenders or requests to participate must be submitted electronically via: https://www.mytenders.co.uk/

I.4)Type of the contracting authority

Body governed by public law

I.5)Main activity

Health

Section II: Object

II.1)Scope of the procurement

II.1.1)Title:

Informatics Service

Reference number: UKBB008

II.1.2)Main CPV code

72310000

II.1.3)Type of contract

Services

II.1.4)Short description:

UK Biobank is issuing this tender to invite bids to supply large-scale, specialist Whole Genome Sequencing (WGS) Vanguard Informatics, for provision of services for core informatics, sample QA/QC and batch reporting, and cohort QA/QC and processing of data to make them research ready, for up to 44,800 genomes.

II.1.5)Estimated total value

II.1.6)Information about lots

This contract is divided into lots: no
II.2)Description
II.2.1)Title:
II.2.2)Additional CPV code(s)

II.2.3)Place of performance

NUTS code: UKD35

II.2.4)Description of the procurement:

UK Biobank is seeking to put in place specialist informatics for the Whole Genome Sequencing vanguard phase, by which the sequencing data generated can be appropriately:

— received, reviewed for data and meta-data quality and integrity, and accepted,

— processed to derive sample-level outputs that will maximise utility to the research community, and

— integrated and quality-controlled at the cohort-level to prepare a research-ready dataset (for example, appropriate for genome-wide association analysis or rare-variant burden testing using common tools).

The successful supplier will receive sequencing output, process these data based on the requirements outlined within this technical specification, and provide deliverable data back to UK Biobank.

UK Biobank has tendered separately for research data storage services to provide long-term storage, access and distribution of these data to the research community and this is outside the scope of services requested here.

The successful supplier must have experience of, and capacity to, supporting projects that involved Informatics services at scale.

During the course of service delivery, industry developments and advice from UK Biobank’s WGS Expert Working Group may suggest changes to the file formats used and/or aspects of the pipeline configuration (both minor and major versions changes and/or alternative or additional pipelines). The successful supplier will need to be able to accommodate any such changes (and which would be agreed and implemented through the project’s change control process).

II.2.5)Award criteria

Criteria below
Quality criterion – Name: Technical requirements / Weighting: 35
Quality criterion – Name: Quality / Weighting: 30
Quality criterion – Name: Cohort-Level QA/QC and Research Readiness / Weighting: 5
Price – Weighting: 30
II.2.6)Estimated value

II.2.7)Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12
This contract is subject to renewal: yes
Description of renewals:

The initial contract term will be 1 year, with the contract starting in March 2019 and the last samples anticipated being sent to the supplier in January 2020. Contract extension may be needed to allow for completion of all informatics for all 44 800 samples.

II.2.10)Information about variants

Variants will be accepted: no

II.2.11)Information about options

Options: no
II.2.12)Information about electronic catalogues

II.2.13)Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: no
II.2.14)Additional information

Section III: Legal, economic, financial and technical information

III.1)Conditions for participation
III.1.1)Suitability to pursue the professional activity, including requirements relating to enrolment on professional or trade registers

III.1.2)Economic and financial standing

Selection criteria as stated in the procurement documents

III.1.3)Technical and professional ability

Selection criteria as stated in the procurement documents
III.1.5)Information about reserved contracts
III.2)Conditions related to the contract
III.2.1)Information about a particular profession
III.2.2)Contract performance conditions:
III.2.3)Information about staff responsible for the performance of the contract

Section IV: Procedure

IV.1)Description

IV.1.1)Type of procedure

Open procedure
IV.1.3)Information about a framework agreement or a dynamic purchasing system
IV.1.4)Information about reduction of the number of solutions or tenders during negotiation or dialogue
IV.1.6)Information about electronic auction

IV.1.8)Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: yes
IV.2)Administrative information
IV.2.1)Previous publication concerning this procedure

IV.2.2)Time limit for receipt of tenders or requests to participate

Date: 26/02/2019
Local time: 12:00
IV.2.3)Estimated date of dispatch of invitations to tender or to participate to selected candidates

IV.2.4)Languages in which tenders or requests to participate may be submitted:

English

IV.2.6)Minimum time frame during which the tenderer must maintain the tender

Tender must be valid until: 24/05/2019

IV.2.7)Conditions for opening of tenders

Date: 26/02/2019
Local time: 12:00

Section VI: Complementary information

VI.1)Information about recurrence

This is a recurrent procurement: no

VI.2)Information about electronic workflows

Electronic invoicing will be accepted
Electronic payment will be used

VI.3)Additional information:

The full tender documents can be downloaded from www.mytenders.co.uk. Completed bids must be submitted though the www.mytenders.co.uk portal.

Note: To register your interest in this notice and obtain any additional information please visit the myTenders website at https://www.mytenders.co.uk/Search/Search_Switch.aspx?ID=214265

The buyer has indicated that it will accept electronic responses to this notice via the Postbox facility.

A user guide is available at https://www.mytenders.co.uk/sitehelp/help_guides.aspx

Suppliers are advised to allow adequate time for uploading documents and to dispatch the electronic response well in advance of the closing time to avoid any last minute problems.

Note: To register your interest in this notice and obtain any additional information please visit the myTenders website at https://www.mytenders.co.uk/Search/Search_Switch.aspx?ID=214642

The buyer has indicated that it will accept electronic responses to this notice via the Postbox facility. A user guide is available at https://www.mytenders.co.uk/sitehelp/help_guides.aspx

Suppliers are advised to allow adequate time for uploading documents and to dispatch the electronic response well in advance of the closing time to avoid any last minute problems.

(MT Ref:214642)

VI.4)Procedures for review

VI.4.1)Review body

UK Biobank Ltd
1-2 Spectrum Way, Adswood
Stockport
SK3 0SA
United Kingdom
Telephone: +44 1614755386Internet address: http://www.ukbiobank.ac.uk
VI.4.2)Body responsible for mediation procedures
VI.4.3)Review procedure
VI.4.4)Service from which information about the review procedure may be obtained

VI.5)Date of dispatch of this notice:

25/01/2019